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Yoshiya Tanaka Selected Research

Member 1 Subfamily B ATP Binding Cassette Transporter

3/2018Relevance of P-glycoprotein on CXCR4+ B cells to organ manifestation in highly active rheumatoid arthritis.
1/2017Role of P-glycoprotein on CD69+CD4+ cells in the pathogenesis of proliferative lupus nephritis and non-responsiveness to immunosuppressive therapy.
1/2017Efficacy of Intravenous Cyclophosphamide Pulse Therapy for P-Glycoprotein-expressing B Cell-associated Active True Renal Lupus Vasculitis in Lupus Nephritis.
11/2015Disease control by regulation of P-glycoprotein on lymphocytes in patients with rheumatoid arthritis.
2/2012Treatment strategy based on targeting P-glycoprotein on peripheral lymphocytes in patients with systemic autoimmune disease.
4/2010Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis.
3/2010Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis.
12/2006Fragmented hyaluronan induces transcriptional up-regulation of the multidrug resistance-1 gene in CD4+ T cells.
6/2005Clinical relevance of the expression of P-glycoprotein on peripheral blood lymphocytes to steroid resistance in patients with systemic lupus erythematosus.
1/2005Overcoming treatment unresponsiveness mediated by P-glycoprotein overexpression on lymphocytes in refractory active systemic lupus erythematosus.
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Yoshiya Tanaka Research Topics

Disease

328Rheumatoid Arthritis
04/2024 - 07/2001
86Systemic Lupus Erythematosus (Libman-Sacks Disease)
04/2024 - 10/2003
50Type 2 Diabetes Mellitus (MODY)
04/2024 - 06/2005
45Infections
04/2024 - 02/2004
37Autoimmune Diseases (Autoimmune Disease)
03/2024 - 02/2002
36Neoplasms (Cancer)
04/2024 - 01/2002
35Osteoporosis
03/2024 - 06/2003
34Inflammation (Inflammations)
04/2024 - 07/2001
26Herpes Zoster
04/2024 - 01/2016
23Psoriatic Arthritis
04/2024 - 07/2016
21Hypoglycemia (Reactive Hypoglycemia)
12/2023 - 02/2006
19Immunoglobulin G4-Related Disease
12/2023 - 02/2012
15Arthritis (Polyarthritis)
03/2024 - 02/2004
15Necrosis
02/2024 - 08/2012
15Pathologic Processes
01/2022 - 03/2002
14Psoriasis (Pustulosis Palmaris et Plantaris)
03/2024 - 01/2004
14Hyperglycemia
12/2023 - 06/2005
14Bone Resorption
10/2023 - 08/2002
13Pain (Aches)
10/2023 - 03/2013
12Rheumatic Diseases (Rheumatism)
09/2020 - 01/2007
11Systemic Scleroderma (Systemic Sclerosis)
04/2024 - 07/2015
10Lupus Nephritis
11/2023 - 01/2016
9Interstitial Lung Diseases (Interstitial Lung Disease)
07/2023 - 06/2002
9Bone Fractures (Bone Fracture)
11/2019 - 06/2003
8Drug-Related Side Effects and Adverse Reactions
12/2023 - 10/2011
8Body Weight (Weight, Body)
11/2023 - 10/2008
8Fibrosis (Cirrhosis)
03/2023 - 10/2009
8Hypercalcemia (Milk Alkali Syndrome)
10/2020 - 01/2004
7Fatigue
01/2024 - 11/2017
7Graves Disease (Basedow Disease)
05/2023 - 01/2014
7Dermatomyositis (Dermatopolymyositis)
11/2022 - 01/2008
7Vascular Calcification
01/2019 - 08/2006
7Diabetes Mellitus
01/2017 - 06/2006
7Atherosclerosis
05/2016 - 05/2003
6Type 1 Diabetes Mellitus (Autoimmune Diabetes)
04/2024 - 01/2015
6Mixed Connective Tissue Disease (MCTD)
04/2024 - 01/2005
6Disease Progression
09/2023 - 07/2004
6Atopic Dermatitis (Atopic Eczema)
08/2023 - 07/2013
6Pulmonary Arterial Hypertension
07/2023 - 01/2020

Drug/Important Bio-Agent (IBA)

87Methotrexate (Mexate)FDA LinkGeneric
03/2024 - 12/2002
54Antirheumatic Agents (DMARD)IBA
04/2024 - 02/2004
53GlucocorticoidsIBA
03/2024 - 06/2003
50Janus Kinase InhibitorsIBA
04/2024 - 01/2012
43Glucose (Dextrose)FDA LinkGeneric
12/2023 - 01/2006
36CytokinesIBA
01/2024 - 07/2001
35Adalimumab (Humira)FDA Link
04/2024 - 06/2012
32baricitinibIBA
07/2023 - 03/2016
31tofacitinibIBA
12/2023 - 08/2011
31Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2023 - 06/2005
28tocilizumab (atlizumab)FDA Link
11/2023 - 04/2011
25Monoclonal AntibodiesIBA
01/2023 - 01/2008
23Tumor Necrosis Factor InhibitorsIBA
04/2024 - 07/2011
22Adrenal Cortex Hormones (Corticosteroids)IBA
01/2022 - 01/2005
21Biomarkers (Surrogate Marker)IBA
04/2024 - 01/2009
21Abatacept (Orencia)FDA Link
11/2023 - 01/2014
21Janus KinasesIBA
10/2023 - 01/2014
19Etanercept (Enbrel)FDA Link
01/2023 - 01/2009
19Interleukin-6 (Interleukin 6)IBA
01/2023 - 11/2007
19Diphosphonates (Bisphosphonates)IBA
05/2021 - 11/2002
18Immunoglobulin G (IgG)IBA
03/2023 - 02/2012
17AutoantibodiesIBA
12/2021 - 12/2002
16peficitinibIBA
12/2023 - 06/2016
16Infliximab (Remicade)FDA Link
11/2021 - 01/2007
15GLPG0634IBA
12/2023 - 01/2021
14upadacitinibIBA
04/2024 - 01/2019
14Prednisolone (Predate)FDA LinkGeneric
04/2024 - 02/2004
14Rituximab (Mabthera)FDA Link
09/2023 - 01/2007
14Insulin (Novolin)FDA Link
11/2022 - 06/2005
14Blood Glucose (Blood Sugar)IBA
01/2022 - 01/2013
13AntibodiesIBA
04/2024 - 06/2011
13DenosumabFDA Link
12/2023 - 05/2010
13Certolizumab PegolFDA Link
07/2023 - 07/2014
12Cyclophosphamide (Cytoxan)FDA LinkGeneric
09/2023 - 10/2003
11DNA (Deoxyribonucleic Acid)IBA
05/2023 - 10/2003
11Member 1 Subfamily B ATP Binding Cassette TransporterIBA
03/2018 - 12/2004
10SteroidsIBA
03/2024 - 10/2003
10belimumabIBA
11/2023 - 01/2018
10anifrolumabIBA
11/2023 - 01/2020
10sarilumabIBA
08/2023 - 09/2014
9Interleukin-17 (Interleukin 17)IBA
03/2024 - 03/2011
9C-Reactive ProteinIBA
12/2023 - 12/2006
9Proteins (Proteins, Gene)FDA Link
10/2023 - 06/2005
9InterferonsIBA
08/2023 - 06/2012
9Hemoglobins (Hemoglobin)IBA
04/2022 - 03/2005
8Vitamin DFDA LinkGeneric
04/2024 - 12/2012
8InterleukinsIBA
03/2024 - 12/2014
7Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
09/2023 - 01/2020
7Phosphotransferases (Kinase)IBA
08/2023 - 11/2012
7Immunosuppressive Agents (Immunosuppressants)IBA
07/2023 - 10/2006
7Hypoglycemic Agents (Hypoglycemics)IBA
01/2022 - 12/2012
7AntigensIBA
01/2021 - 08/2002
7Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
12/2020 - 04/2013
6bimekizumabIBA
02/2024 - 01/2023
6LipidsIBA
02/2023 - 10/2008
6quetmolimabIBA
01/2023 - 01/2018

Therapy/Procedure

166Therapeutics
03/2024 - 09/2002
10Remission Induction
01/2023 - 02/2004
9Glycemic Control
02/2023 - 06/2006
8Precision Medicine
04/2023 - 07/2016
6Drug Therapy (Chemotherapy)
03/2023 - 07/2004